Thanks to Chief Family Officer, I saved a bundle today at Safeway.
For every $30 (Before Coupons!) you spend on products designated Living Well, you will receive a $10 Catalina coupon at checkout. That's effectively getting $30 of groceries for only $20. Now, if you also use some coupons, you get even better savings.
I stocked up on Electrosol dishwasher soap and pasta sauces; the detailed list of participating brands is here. Note that not all varieties of each brand will count toward the $30 total so check the signs carefully.